Patrice Evra scored his first goal for Juventus but their 25-match winning run at home in Serie A was ended by Sampdoria.
Left-back Evra, a summer signing from Manchester United, put the league leaders ahead when he headed home Claudio Marchisio’s corner.
But substitute Manolo Gabbiadini, who is co-owned by Juve, levelled with a curling effort from 18 yards.
Gabbiadini almost scored a late winner but Gianluigi Buffon kept out his shot.
The draw – Juventus’s second in a row – means the champions now only lead second-placed Roma by one point following their victory over Genoa.
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Source: BBC Sport